{"id":39,"date":"2026-05-14T08:35:55","date_gmt":"2026-05-14T08:35:55","guid":{"rendered":"https:\/\/zunkelab.de\/?page_id=39"},"modified":"2026-05-15T20:09:16","modified_gmt":"2026-05-15T20:09:16","slug":"welcome-to-zunkelab","status":"publish","type":"page","link":"https:\/\/zunkelab.de\/","title":{"rendered":"Welcome to Zunkelab!"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"39\" class=\"elementor elementor-39\">\n\t\t\t\t<div class=\"elementor-element elementor-element-592d449 e-con e-atomic-element e-flexbox-base e-19b6351 \" data-id=\"592d449\" data-element_type=\"e-flexbox\" data-e-type=\"e-flexbox\" data-interaction-id=\"592d449\">\n    \t\t<div class=\"elementor-element elementor-element-d962eda elementor-widget elementor-widget-html\" data-id=\"d962eda\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<section class=\"home-slider\">\n\n  <div class=\"home-slide active slide-1\">\n    <div class=\"home-slide-content center\">\n      <span>Welcome<\/span>\n      <h1>\ud83d\udd2c Welcome to the Zunke Lab<\/h1>\n      <p>\n        We study the molecular mechanisms of neurodegeneration with a focus on Parkinson\u2019s disease.\n      <\/p>\n    <\/div>\n  <\/div>\n\n  <div class=\"home-slide slide-2\">\n    <div class=\"home-slide-content left\">\n      <span>Research<\/span>\n      <h1>Our Research<\/h1>\n      <p>\n        Lysosomal biology \u2022 Alpha-synuclein \u2022 Biomarkers \u2022 Astrocytes\n      <\/p>\n    <\/div>\n  <\/div>\n\n  <div class=\"home-slide slide-3\">\n    <div class=\"home-slide-content right\">\n      <span>Parkinson\u2019s Disease<\/span>\n      <h1>Advancing Parkinson\u2019s Disease Research<\/h1>\n      <p>\n        Exploring disease mechanisms to better understand neurodegeneration and support future therapeutic strategies.\n      <\/p>\n      <div class=\"home-slide-sticker\">Brain Biology<\/div>\n    <\/div>\n  <\/div>\n\n  <div 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<span>About the Lab<\/span>\n    <h2>Exploring cellular pathways in neurodegeneration<\/h2>\n    <p>\n      The Zunke Lab investigates how lysosomal function, protein aggregation, extracellular vesicles and glial cell biology contribute to neurodegenerative diseases such as Parkinson\u2019s disease. Our goal is to uncover disease mechanisms and translate these findings into new diagnostic and therapeutic strategies.\n    <\/p>\n  <\/div>\n\n  <!-- Research Topics -->\n  <div class=\"topic-grid\">\n\n    <article class=\"topic-card\">\n      <div class=\"topic-image\">\n        <img decoding=\"async\" src=\"https:\/\/zunkelab.de\/wp-content\/uploads\/2026\/05\/EVs.png\" alt=\"Extracellular vesicles\">\n      <\/div>\n      <div class=\"topic-content\">\n        <span>01<\/span>\n        <h3>What are EVs?<\/h3>\n        <p>\n          Extracellular vesicles are small particles released by cells that carry proteins, RNA and other molecular signals. We study how EVs can reflect disease-related changes and serve as potential biomarkers for Parkinson\u2019s disease.\n        <\/p>\n      <\/div>\n    <\/article>\n\n    <article class=\"topic-card\">\n      <div class=\"topic-image\">\n        <img decoding=\"async\" src=\"https:\/\/zunkelab.de\/wp-content\/uploads\/2026\/05\/aSyn-and-cathepsins_Crosstalk.png\" alt=\"Cathepsin mechanisms\">\n      <\/div>\n      <div class=\"topic-content\">\n        <span>02<\/span>\n        <h3>Mechanisms of cathepsins<\/h3>\n        <p>\n          Cathepsins are lysosomal proteases that help degrade and clear cellular proteins. We investigate how these enzymes influence \u03b1-synuclein turnover and whether enhancing lysosomal activity can reduce toxic protein aggregation.\n        <\/p>\n      <\/div>\n    <\/article>\n\n    <article class=\"topic-card\">\n      <div class=\"topic-image\">\n        <img decoding=\"async\" src=\"https:\/\/zunkelab.de\/wp-content\/uploads\/2026\/05\/astrocytes.png\" alt=\"Astrocytes and neuroinflammation\">\n      <\/div>\n      <div class=\"topic-content\">\n        <span>03<\/span>\n        <h3>Glial cells & neuroinflammation<\/h3>\n        <p>\n          Astrocytes and other glial cells play key roles in brain homeostasis, inflammation and neuronal support. We explore how glial responses change during disease and whether they can become therapeutic targets.\n        <\/p>\n      <\/div>\n    <\/article>\n\n  <\/div>\n\n  <!-- Team Image Section -->\n  <section class=\"team-highlight-section\">\n\n    <div class=\"team-highlight-image\">\n      <img decoding=\"async\" src=\"https:\/\/zunkelab.de\/wp-content\/uploads\/2026\/05\/DSC08185.jpg\" alt=\"Zunke Lab team\">\n    <\/div>\n\n    <div class=\"team-highlight-text\">\n      <span>Our Team<\/span>\n      <h2>Science is collaborative<\/h2>\n      <p>\n        Our interdisciplinary and international team combines expertise in cell biology, neuroscience, molecular medicine and translational research to better understand neurodegenerative disease mechanisms.\n      <\/p>\n\n    <\/div>\n\n  <\/section>\n\n<\/section>\n\n<style>\n  .home-content-section {\n    width: 100%;\n    max-width: 1120px;\n    margin: 42px auto;\n    color: #3a2618;\n  }\n\n  .home-intro-card {\n    background: 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999px;\n    text-decoration: none;\n    font-size: 14px;\n    font-weight: 800;\n    transition: all 0.25s ease;\n  }\n\n  .team-highlight-text a:hover {\n    background: #e28a3b;\n    transform: translateY(-2px);\n  }\n\n  @media (max-width: 980px) {\n    .topic-grid {\n      grid-template-columns: 1fr;\n    }\n\n    .team-highlight-section {\n      grid-template-columns: 1fr;\n    }\n\n    .team-highlight-image,\n    .team-highlight-image img {\n      min-height: 300px;\n    }\n  }\n\n  @media (max-width: 767px) {\n    .home-content-section {\n      margin: 28px auto;\n    }\n\n    .home-intro-card,\n    .team-highlight-text {\n      padding: 24px;\n    }\n\n    .home-intro-card,\n    .topic-card,\n    .team-highlight-section {\n      border-radius: 20px;\n    }\n\n    .home-intro-card h2,\n    .team-highlight-text h2 {\n      font-size: 30px;\n    }\n\n    .topic-image {\n      height: 190px;\n    }\n  }\n<\/style>\t\t\t\t<\/div>\n\t\t\n<\/div>\n<div class=\"elementor-element elementor-element-3d1ed57 e-flex e-con-boxed e-con e-parent\" data-id=\"3d1ed57\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7f1fcef elementor-widget elementor-widget-html\" data-id=\"7f1fcef\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<section class=\"lab-gallery-section\">\n\n  <div class=\"lab-gallery-heading-box\">\n    <span>Behind the Scenes<\/span>\n    <h2>Us doing research-ish things<\/h2>\n  <\/div>\n\n  <div class=\"lab-gallery-slider\">\n\n    <div class=\"lab-slide\">\n      <img decoding=\"async\" src=\"https:\/\/zunkelab.de\/wp-content\/uploads\/2026\/05\/lab.jpg\" alt=\"Lab team doing research\">\n      <div class=\"lab-caption\">\n        <span>01<\/span>\n        <p>Advancing research through teamwork and expertise.<\/p>\n      <\/div>\n    <\/div>\n\n    <div class=\"lab-slide\">\n      <img decoding=\"async\" src=\"https:\/\/zunkelab.de\/wp-content\/uploads\/2026\/05\/Labrobinjohannes.jpg\" alt=\"Lab team in the laboratory\">\n      <div class=\"lab-caption\">\n        <span>02<\/span>\n        <p>Experimental work and scientific exchange.<\/p>\n      <\/div>\n    <\/div>\n\n    <div class=\"lab-slide\">\n      <img decoding=\"async\" src=\"https:\/\/zunkelab.de\/wp-content\/uploads\/2026\/05\/DSC00155.jpg\" alt=\"Researchers working in the lab\">\n      <div class=\"lab-caption\">\n        <span>03<\/span>\n        <p>Hands-on research in cellular and molecular biology.<\/p>\n      <\/div>\n    <\/div>\n\n    <div class=\"lab-slide\">\n      <img decoding=\"async\" src=\"https:\/\/zunkelab.de\/wp-content\/uploads\/2026\/05\/DSC00163.jpg\" alt=\"Lab research moment\">\n      <div class=\"lab-caption\">\n        <span>04<\/span>\n        <p>Laboratory-based research.<\/p>\n      <\/div>\n    <\/div>\n\n  <\/div>\n\n<\/section>\n\n<style>\n  .lab-gallery-section {\n    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   }\n  }\n<\/style>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-67cc7fd e-con e-atomic-element e-flexbox-base e-0927f14 \" data-id=\"67cc7fd\" data-element_type=\"e-flexbox\" data-e-type=\"e-flexbox\" data-interaction-id=\"67cc7fd\">\n    \t\t<div class=\"elementor-element elementor-element-2e2ce5b elementor-widget elementor-widget-html\" data-id=\"2e2ce5b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<section\n  class=\"partners-section\"\n  style=\"\n    padding: 80px 24px;\n    text-align: center;\n    background: #ffffff;\n  \"\n>\n  <div\n    style=\"\n      max-width: 1100px;\n      margin: 0 auto;\n    \"\n  >\n    <span\n      style=\"\n        display: inline-block;\n        margin-bottom: 12px;\n        font-size: 13px;\n        letter-spacing: 0.12em;\n        text-transform: uppercase;\n        font-weight: 600;\n        color: #777;\n      \"\n    >\n      Network\n    <\/span>\n\n    <h2\n      style=\"\n        margin: 0 0 16px;\n        font-size: clamp(32px, 5vw, 56px);\n        line-height: 1.1;\n        color: #111;\n      \"\n    >\n      Collaboration and Project Partners\n    <\/h2>\n\n    <p\n      style=\"\n        max-width: 700px;\n        margin: 0 auto 42px;\n        font-size: 17px;\n        line-height: 1.6;\n        color: #555;\n      \"\n    >\n      Our research is strengthened through collaborations with clinical, scientific, and translational partners.\n    <\/p>\n\n    <div\n      style=\"\n        background: #f7f7f7;\n        border-radius: 22px;\n        padding: 32px;\n        display: flex;\n        align-items: center;\n        justify-content: center;\n      \"\n    >\n      <img decoding=\"async\"\n        src=\"https:\/\/zunkelab.de\/wp-content\/uploads\/2026\/05\/fundings3.png\"\n        alt=\"Collaboration and project partners\"\n        style=\"\n          width: 100%;\n          max-width: 950px;\n          height: auto;\n          display: block;\n          object-fit: contain;\n        \"\n      >\n    <\/div>\n  <\/div>\n<\/section>\t\t\t\t<\/div>\n\t\t\n<\/div>\n\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Welcome \ud83d\udd2c Welcome to the Zunke Lab We study the molecular mechanisms of neurodegeneration with a focus on Parkinson\u2019s disease. Research Our Research Lysosomal biology \u2022 Alpha-synuclein \u2022 Biomarkers \u2022 Astrocytes Parkinson\u2019s Disease Advancing Parkinson\u2019s Disease Research Exploring disease mechanisms to better understand neurodegeneration and support future therapeutic strategies. Brain Biology About the Lab Exploring [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":42,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-39","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/zunkelab.de\/index.php?rest_route=\/wp\/v2\/pages\/39","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zunkelab.de\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/zunkelab.de\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/zunkelab.de\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/zunkelab.de\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=39"}],"version-history":[{"count":47,"href":"https:\/\/zunkelab.de\/index.php?rest_route=\/wp\/v2\/pages\/39\/revisions"}],"predecessor-version":[{"id":302,"href":"https:\/\/zunkelab.de\/index.php?rest_route=\/wp\/v2\/pages\/39\/revisions\/302"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zunkelab.de\/index.php?rest_route=\/wp\/v2\/media\/42"}],"wp:attachment":[{"href":"https:\/\/zunkelab.de\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=39"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}